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Crystal structure of a homogeneous IgG-Fc glycoform with the N-glycan designed to maximize the antibody dependent cellular cytotoxicity.

2017

Chen CL, Hsu JC, Lin CW, Wang CH, Tsai MH, Wu CY, Wong CH*, Ma C*

ACS Chemical Biology, 12(5), 1335-1345.

Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines.

2015

Wu HH, Hwang-Verslues WW, Lee WH, Huang CK, Wei PC, Chen CL, Shew JY, Lee EY, Jeng YM, Tien YW, Ma C, Lee WH*

The Journal of experimental medicine, 212(3), 333-349.

A common glycan structure on immunoglobulin G for enhancement of effector functions.

2015

Lin CW, Tsai MH, Li ST, Tsai TI, Chu KC, Liu YC, Lai MY, Wu CY, Tseng YC, Shivatare SS, Wang CH, Chao P, Wang SY, Shih HW, Zeng YF, You TH, Liao JY, Tu YC, Lin YS, Chuang HY, Chen CL, Tsai CS, Huang CC, Lin NH, Ma C, Wu CY*, Wong CH*

Proceedings of the National Academy of Sciences of the United States of America, 112(34), 10611-6.

Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections.

2014

Chen JR, Yu YH, Tseng YC, Chiang WL, Chiang MF, Ko YA, Chiu YK, Ma HH, Wu CY, Jan JT, Lin KI*, Ma C*, Wong CH*

Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2476-2481.

Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-kB-mediated antiapoptotic pathway.

2013

Huang CK, Yang CY, Jeng YM, Chen CL, Wu HH, Chang YC, Ma C, Kuo WH, Chang KJ, Shew JY and Lee WH*

Oncogene, (2013), 1-10.

Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism.

2012

Huang CY, Shih HW, Lin LY, Tien YW, Cheng TJR, Cheng WC, Wong CH*, and Ma C*

Proceedings of the National Academy of Sciences of the United States of America, 109(17), 6496-6501.

Vaccine design of hemagglutinin glycoprotein against influenza.

2011

Chen JR, Ma C*, Wong CH*

Trends in Biotechnology, 29, 426-434.

Glycans on influenza hemagglutinin affect receptor binding and immune response.

2009

Wang CC, Chen JR, Tseng YC, Hsu CH, Hung YF, Chen SW, Chen CM, Khoo KH, Cheng TJ, Cheng YSE, Jan JT, Wu CY, Ma C* and Wong CH*

Proceedings of the National Academy of Sciences of the United States of America, 106, 18137-18142.

Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.

2009

Sung MT, Lai YT, Huang CY, Chou LY, Shih HW, Cheng WC, Wong CH* and Ma C*

Proceedings of the National Academy of Sciences of the United States of America, 106, 8824-8829.

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